So what’s the massive problem with Deadpool’s powers? Because Wade’s cancer (like every part of his body) inherited the same DNA, any mutant genes — and superpowers — would be activated in his tumor cells too. Deadpool would have super-cancer.
Since his debut in Captain America: The First Avenger, Bucky Barnes has had one of the most compelling, and complicated, character arcs in the entire Marvel Cinematic Universe, being both a villain and a hero at different points in his journey.